Despite successful vaccine development, there are still no effective drugs for most viral diseases. This should change as soon as possible. With the project iGUARD (integrated Guided Ultrafast Antiviral RNAi Drug development) a research team of Prof. Armin Braun, Fraunhofer ITEM, and Prof. Axel Schambach, Hannover Medical School (MHH), is developing RNA-based drugs to combat viral diseases using a natural mechanism of our body.